Although most U.S. airports use the same three-letter location identifier for the FAA and IATA, Marco Island Airport is assigned MKY by the FAA and MRK by the IATA (which assigned MKY to Mackay Airport in Mackay, Queensland, Australia). The airport's ICAO identifier is KMKY.

Marco Island Airport covers an area of 140 acres (57 ha) and contains one asphalt runway (17/35): 5,000 x 100 ft (1,524 x 30 m).

For 12-month period ending August 25, 1998, the airport had 14,580 aircraft operations, an average of 39 per day: 99% general aviation (14,560) and 1% military (20). There are 36 aircraft based at this airport: 83% single engine (30), 8% multi engine (3), 6% jet aircraft (2) and 3% helicopters (1).